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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PPEF2 All Species: 12.42
Human Site: S357 Identified Species: 24.85
UniProt: O14830 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O14830 NP_006230.2 753 86518 S357 E S R S L P S S P L R L G S Y
Chimpanzee Pan troglodytes XP_526584 753 86517 S357 E S R S L P S S P L R L G S Y
Rhesus Macaque Macaca mulatta XP_001100042 753 86580 S357 Q S R S L P S S P L R L S S Y
Dog Lupus familis XP_544934 970 109306 D503 L H L A T L V D E K V L I L H
Cat Felis silvestris
Mouse Mus musculus O35385 757 86627 S357 Q S R S L P S S P F H L G S G
Rat Rattus norvegicus Q3SWT6 640 73948 K259 Q K Y K L H G K K I L Q V L E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510316 925 101565 P445 R K L P R G K P R T Y L T G S
Chicken Gallus gallus XP_420595 713 82896 I332 E L N R N V E I K E I N G E S
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001108202 718 82122 N337 C S R S S S R N R G R N S R S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P40421 661 75493 L280 G F S D S T S L D L I K S I D
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_780182 694 79630 K313 S V L K P P L K E G A E E L T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa Q9UW86 308 35549
Conservation
Percent
Protein Identity: 100 99.1 95.4 55 N.A. 82.6 43 N.A. 26 66.2 N.A. 52.5 N.A. 29.3 N.A. N.A. 36.2
Protein Similarity: 100 99.8 97.7 62.4 N.A. 90.8 61.6 N.A. 37.7 77.5 N.A. 66.2 N.A. 46.3 N.A. N.A. 52.9
P-Site Identity: 100 100 86.6 6.6 N.A. 73.3 6.6 N.A. 6.6 13.3 N.A. 26.6 N.A. 13.3 N.A. N.A. 6.6
P-Site Similarity: 100 100 93.3 20 N.A. 80 20 N.A. 6.6 13.3 N.A. 33.3 N.A. 13.3 N.A. N.A. 6.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. 20.1
Protein Similarity: N.A. N.A. N.A. N.A. N.A. 29.2
P-Site Identity: N.A. N.A. N.A. N.A. N.A. 0
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. 0
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 9 0 0 0 0 0 0 9 0 0 0 0 % A
% Cys: 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 9 0 0 0 9 9 0 0 0 0 0 9 % D
% Glu: 25 0 0 0 0 0 9 0 17 9 0 9 9 9 9 % E
% Phe: 0 9 0 0 0 0 0 0 0 9 0 0 0 0 0 % F
% Gly: 9 0 0 0 0 9 9 0 0 17 0 0 34 9 9 % G
% His: 0 9 0 0 0 9 0 0 0 0 9 0 0 0 9 % H
% Ile: 0 0 0 0 0 0 0 9 0 9 17 0 9 9 0 % I
% Lys: 0 17 0 17 0 0 9 17 17 9 0 9 0 0 0 % K
% Leu: 9 9 25 0 42 9 9 9 0 34 9 50 0 25 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 9 0 9 0 0 9 0 0 0 17 0 0 0 % N
% Pro: 0 0 0 9 9 42 0 9 34 0 0 0 0 0 0 % P
% Gln: 25 0 0 0 0 0 0 0 0 0 0 9 0 0 0 % Q
% Arg: 9 0 42 9 9 0 9 0 17 0 34 0 0 9 0 % R
% Ser: 9 42 9 42 17 9 42 34 0 0 0 0 25 34 25 % S
% Thr: 0 0 0 0 9 9 0 0 0 9 0 0 9 0 9 % T
% Val: 0 9 0 0 0 9 9 0 0 0 9 0 9 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 9 0 0 0 0 0 0 0 9 0 0 0 25 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _